5-Nitro-1,10-phenanthroline
- Name 5-Nitro-1,10-phenanthroline
- CAS 4199-88-6
- Purity 99%
Product Details
Cost-effective and customizable 5-Nitro-1,10-phenanthroline 4199-88-6 supplier
- Molecular Formula: C12H7N3O2
- Molecular Weight: 225.206
- Appearance/Colour: Pale yellow or brown solid
- Vapor Pressure: 8.08E-12mmHg at 25°C
- Melting Point: 202-204 ºC (lit.)
- Refractive Index: 1.5700 (estimate)
- Boiling Point: 444ºC at 760 mmHg
- PKA: pK1:3.232(+1) (25°C)
- Flash Point: 222.3 ºC
- PSA： 71.60000
- Density: 1.444 g/cm3
- LogP: 3.21440
5-Nitro-1,10-phenanthroline(Cas 4199-88-6) Usage
|
Biochem/physiol Actions |
Platinum chelates of a variety of 5-substituted phenanthrolines, including 5-Nitro-1,10-phenanthroline, were tested for cytotoxicity against L1210 murine leukemia cells. Though all tested compounds had very similar DNA-binding affinities, they exhibited a wide range of cytotoxicity. |
|
Purification Methods |
Crystallise the phenanthroline from *benzene/pet ether, until anhydrous. It also crystallises from H2O with m 202o, and EtOAc with m 203o. Its pK2 5 varies from 3.20 to 2.69 with varying MeOH/H2O ratios from 0 to 0.95 moles/L, and from 3.20 to 1.95 in varying EtOH/H2O ratios from 0 to 0.94 moles/L [Ram et al. J Prakt Chem 319 719 1977]. It forms complexes with Cu2+, Zn2+, In2+, Fe2+ , Co2+, Ni2+ . [Beilstein 23 III/IV 1682, 23/8 V 425.] |
InChI:InChI=1/C12H7N3O2.H2O/c16-15(17)10-7-8-3-1-5-13-11(8)12-9(10)4-2-6-14-12;/h1-7H;1H2
4199-88-6 Relevant articles
-
Inglett,Smith
, p. 842 (1950)
-
Synthesis, photophysical properties, and theoretical studies on pyrrole-containing bromo Re(I) complex
Si, Zhenjun,Li, Xiaona,Li, Xiyan,Zhang, Hongjie
, p. 3742 - 3748 (2009)
Two bromo rhenium(I) carbonyl complexes ...
Luminescent ruthenium(II) polypyridyl functionalized gold nanoparticles; Their DNA binding abilities and application as cellular imaging agents
Elmes, Robert B. P.,Orange, Kim N.,Cloonan, Suzanne M.,Williams, D. Clive,Gunnlaugsson, Thorfinnur
, p. 15862 - 15865 (2011)
The synthesis and photophysical and biol...
A shining proposal for the detection of dissolved O2 in aqueous medium: Self-calibrated optical sensing via a covalent hybrid structure of carbon-dots&Ru
Jiang, Yuanyuan,Liu, Liang,Liu, Xuelian,Mao, Li,Wang, Hongjun,Zhao, Yanping
, (2021)
O2 is a life-supporting gas and has been...
Synthesis and characterization of a Eu-containing polymer precursor featuring thenoyltrifluoroacetone and 5-acrylamido-1,10-phenanthroline
Xu, Cun-Jin,Li, Bo-Geng,Wan, Jin-Tao,Bu, Zhi-Yang
, p. 159 - 163 (2011)
A polymerizable ligand, 5-acrylamido-1,1...
Synthesis and characterization of luminescent SiO2@Eu(phen–Si) core–shell nanospheres
Li, Wen-Xian,Zheng, Yu-Shan,Zhang, Hong-Bo,Bao, Jin-Rong,Li, Yi-Lian,Ma, Yang-Yang,Feng, Li-Na,Feng, Shu-Yan
, p. 250 - 259 (2020)
Four core–shell structured nanometre lum...
In situ generation of self-enhanced luminophore by β-lactamase catalysis for highly sensitive electrochemiluminescent aptasensor
Gui, Guo-Feng,Zhuo, Ying,Chai, Ya-Qin,Xiang, Yun,Yuan, Ruo
, p. 5873 - 5880 (2014)
This work described a new electrogenerat...
Preparation and valence tautomeric behavior of a cobaltdioxolene complex with a new TTF-functionalized phenanthroline Ligand
Kanegawa, Shinji,Kang, Soonchul,Sato, Osamu
, p. 700 - 702 (2013)
In this study, a new tetrathiafulvalene-...
SYNTHESIS OF POLYMERS CONTAINING o-PHENANTHROLINE GROUPS AND STUDY OF THEIR COMPLEXING WITH COPPER(II) IONS
Shamshinova, V. V.,Kokorin, A. I.,Kolosova, E. M.,Yaroslavov, A. A.
, p. 2476 - 2479 (1986)
-
Memristors Based on an Iridium(III) Complex Containing Viologen for Advanced Synaptic Bionics
Chen, Xintong,Deng, Yongjing,Li, Feiyang,Liu, Shujuan,Tong, Yi,Wang, Yu,Zhao, Qiang,Zhuang, Yanling
, p. 13021 - 13028 (2021)
Memristors with nonvolatile memory prope...
A highly selective off-on red-emitting phosphorescent thiol probe with large stokes shift and long luminescent lifetime
Ji, Shaomin,Guo, Huimin,Yuan, Xiaolin,Li, Xiaohuan,Ding, Haidong,Gao, Peng,Zhao, Chunxia,Wu, Wenting,Wu, Wanhua,Zhao, Jianzhang
, p. 2876 - 2879 (2010)
(Figure presented) An OFF-ON red-emittin...
Photophysical properties of lanthanide complexes with 5-nitro-1,10- phenanthroline
Xu, Cunjin
, p. 631 - 635 (2010)
Five novel lanthanide (Eu3+, Tb3+, Sm 3+...
A novel white-luminescent ternary europium hybrids with phenanthroline functionalized periodic mesoporous organosilicas (PMOs) and 2-methyl-9- hydroxyphenalenone
Yan, Bing,Gu, Yan-Jing
, p. 75 - 78 (2013)
The molecular linkage (phenSi) is modifi...
Europium (III) complex functionalized Si-MCM-41 hybrid materials with visible-light-excited luminescence
Gu, Yan-Jing,Yan, Bing
, p. 96 - 102 (2013)
The synthesis of organics 9-hydroxyphena...
Meta Selective C-H Borylation of Sterically Biased and Unbiased Substrates Directed by Electrostatic Interaction
Chaturvedi, Jagriti,Haldar, Chabush,Bisht, Ranjana,Pandey, Gajanan,Chattopadhyay, Buddhadeb
supporting information, p. 7604 - 7611 (2021/05/26)
An electrostatically directed meta boryl...
Molecular engineering for optical properties of 5-substituted-1,10-phenanthroline-based Ru(ii) complexes
Beley, Marc,Blanchard-Desce, Mireille,Chevreux, Sylviane,Gros, Philippe C.,Lawson-Daku, Latévi Max,Lemercier, Gilles,Mongin, Olivier,Moreau, Juliette,Rousset, Elodie
, p. 10119 - 10132 (2021/08/03)
A series of homo- and heteroleptic Ru(ii...
Ionic iridium (III) complex containing viologen units and preparation method and application thereof
-
Paragraph 0035-0036; 0039, (2021/04/03)
The invention discloses an ionic iridium...
4199-88-6 Process route
-
-
66-71-7
1,10-Phenanthroline
-
-
4199-88-6
5-Nitro-1,10-phenanthroline
| Conditions | Yield |
|---|---|
|
With
sulfuric acid; nitric acid;
at 160 ℃;
for 3h;
|
100%
|
|
With
sulfuric acid; nitric acid;
at 160 ℃;
|
99%
|
|
With
sulfuric acid; nitric acid;
at 160 ℃;
for 3h;
|
99%
|
|
With
sulfuric acid; nitric acid;
at 160 ℃;
for 3h;
|
99%
|
|
With
sulfuric acid; nitric acid;
at 160 ℃;
for 3h;
Inert atmosphere;
|
91.5%
|
|
With
fuming sulphuric acid; nitric acid;
at 160 - 170 ℃;
|
91%
|
|
With
sulfuric acid; nitric acid;
at 0 - 150 ℃;
for 3h;
|
90%
|
|
With
sulfuric acid; nitric acid;
for 3h;
Inert atmosphere;
Schlenk technique;
Reflux;
|
90%
|
|
With
sulfuric acid; nitric acid;
at 160 ℃;
for 3h;
|
88%
|
|
With
sulfuric acid; nitric acid;
In
water;
at 170 ℃;
for 3h;
|
86%
|
|
1,10-Phenanthroline;
With
sulfuric acid; nitric acid;
In
water;
at 100 - 110 ℃;
With
sodium hydroxide;
In
water;
at 20 ℃;
pH=6 - 7;
|
68%
|
|
With
sulfuric acid; nitric acid;
at 120 ℃;
for 3h;
|
65%
|
|
With
sulfuric acid; nitric acid;
at 100 - 110 ℃;
for 2h;
|
63%
|
|
With
sulfuric acid; nitric acid;
at 90 ℃;
for 30h;
|
63%
|
|
With
sulfuric acid; nitric acid;
|
60%
|
|
1,10-Phenanthroline;
With
sulfuric acid; sulfur trioxide; nitric acid;
With
sodium hydrogencarbonate;
|
60%
|
|
With
sulfuric acid; nitric acid;
at 170 ℃;
for 0.5h;
|
56%
|
|
With
sulfuric acid; nitric acid;
at 150 - 170 ℃;
for 3h;
|
24%
|
|
With
sulfuric acid; nitric acid;
|
|
|
With
sulfuric acid; nitric acid;
at 160 - 170 ℃;
for 2h;
|
|
|
With
sulfuric acid; nitric acid;
|
|
|
With
sulfuric acid; nitric acid;
In
water;
|
|
|
With
sulfuric acid; nitric acid;
for 3h;
Reflux;
|
|
|
With
sulfuric acid; nitric acid;
|
|
|
With
sulfuric acid; nitric acid;
at 170 ℃;
|
|
|
With
sulfuric acid; nitric acid;
|
|
|
With
sulfuric acid; nitric acid;
Reflux;
|
|
|
With
sulfuric acid; nitric acid;
at 165 ℃;
for 3h;
|
|
|
With
sulfuric acid; nitric acid;
at 165 ℃;
for 4h;
|
|
|
With
sulfuric acid; nitric acid;
at 160 ℃;
for 3h;
|
|
|
With
sulfuric acid; nitric acid;
at 165 ℃;
for 2h;
|
-
-
630067-06-0
1,10-phenanthroline-5-carboxylic acid
-
-
4199-88-6
5-Nitro-1,10-phenanthroline
| Conditions | Yield |
|---|---|
|
With
nitronium tetrafluoborate; silver carbonate;
In
N,N-dimethyl acetamide;
at 90 ℃;
for 12h;
regioselective reaction;
Inert atmosphere;
Schlenk technique;
|
81%
|
4199-88-6 Upstream products
-
66-71-7
1,10-Phenanthroline
-
42606-38-2
8-amino-5-nitroquinoline
-
56-81-5
glycerol
-
7664-93-9
sulfuric acid
4199-88-6 Downstream products
-
54258-41-2
1,10-phenanthroline-5-amine
-
168646-53-5
5-nitro-6-amino-1,10-phenanthroline
-
111047-29-1
2-iodo-N-1,10-phenanthrolin-5-ylacetamide
-
229622-33-7
[Cu(5-nitro-1,10-phenanthroline)(salicylaldehydate)]NO3
Related products
-
Sulphur Yellow 2CAS：1326-66-5
-
-
2-butoxyethyl didecyl phosphiteCAS：94006-31-2
-
2,6-Octadien-1-ol,3,7-dimethyl-, 1-formate, (2E)-CAS：105-86-2