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4-Pyridineethanol

  • Name 4-Pyridineethanol
  • CAS 5344-27-4
  • Purity 99%
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Product Details

Top Quality 4-Pyridineethanol 5344-27-4 Hot Sell In Stock

  • Molecular Formula: C7H9 N O
  • Molecular Weight: 123.155
  • Vapor Pressure: 0.0165mmHg at 25°C 
  • Melting Point: 8-10°C 
  • Refractive Index: 1.5380 
  • Boiling Point: 121-122°C 2mm 
  • PKA: 14.51±0.10(Predicted) 
  • Flash Point: 101.5°C 
  • PSA: 33.12000 
  • Density: 1.09g/cm3 
  • LogP: 0.61640 

4-Pyridineethanol(Cas 5344-27-4) Usage

Safety Profile

Poison by intravenous route. Moderately toxic by ingestion. When heated to decomposition it emits toxic fumes of NOx.

InChI:InChI=1/C7H9NO/c9-6-3-7-1-4-8-5-2-7/h1-2,4-5,9H,3,6H2

5344-27-4 Relevant articles

Radical Hydroarylation of Functionalized Olefins and Mechanistic Investigation of Photocatalytic Pyridyl Radical Reactions

Seath, Ciaran P.,Vogt, David B.,Xu, Zihao,Boyington, Allyson J.,Jui, Nathan T.

, p. 15525 - 15534 (2018/11/23)

We report the photoredox alkylation of h...

Discovery of Potent Human Glutaminyl Cyclase Inhibitors as Anti-Alzheimer’s Agents Based on Rational Design

Hoang, Van-Hai,Tran, Phuong-Thao,Cui, Minghua,Ngo, Van T. H.,Ann, Jihyae,Park, Jongmi,Lee, Jiyoun,Choi, Kwanghyun,Cho, Hanyang,Kim, Hee,Ha, Hee-Jin,Hong, Hyun-Seok,Choi, Sun,Kim, Young-Ho,Lee, Jeewoo

supporting information, p. 2573 - 2590 (2017/04/03)

Glutaminyl cyclase (QC) has been implica...

Nucleophilic addition of arylmethylzinc reagents (ArCH2ZnCl) to formaldehyde: An easy access to 2-(hetro)arylethyl alcohols

Bhatt,Samant,Pednekar, Suhas

supporting information, p. 968 - 974 (2017/05/04)

The selective addition of arylmethylmagn...

(N -Phosphinoamidinate)Iron pre-catalysts for the room temperature hydrosilylation of carbonyl compounds with broad substrate scope at low loadings

Ruddy, Adam J.,Kelly, Colin M.,Crawford, Sarah M.,Wheaton, Craig A.,Sydora, Orson L.,Small, Brooke L.,Stradiotto, Mark,Turculet, Laura

supporting information, p. 5581 - 5588 (2013/11/06)

The synthesis and structural characteriz...

5344-27-4 Process route

4-(Chloromethyl)pyridine
10445-91-7

4-(Chloromethyl)pyridine

formaldehyd
50-00-0,30525-89-4,61233-19-0

formaldehyd

4-(2-hydroxyethyl)pyridine
5344-27-4

4-(2-hydroxyethyl)pyridine

Conditions
Conditions Yield
4-(Chloromethyl)pyridine; With chloro-trimethyl-silane; ethylene dibromide; zinc; In tetrahydrofuran; at 70 ℃; for 2h; Schlenk technique; Inert atmosphere;
formaldehyd; In tetrahydrofuran; at 70 ℃; for 6h; Schlenk technique; Inert atmosphere;
71%
pyridin-4-yl-acetic acid ethyl ester
54401-85-3

pyridin-4-yl-acetic acid ethyl ester

4-(2-hydroxyethyl)pyridine
5344-27-4

4-(2-hydroxyethyl)pyridine

Conditions
Conditions Yield
With lithium aluminium tetrahydride; In diethyl ether;
78%
With lithium aluminium tetrahydride; diethyl ether;
In tetrahydrofuran; water;
pyridin-4-yl-acetic acid ethyl ester; With C33H58FeN3PSi2; phenylsilane; In toluene; at 20 ℃; for 4h; Inert atmosphere; Glovebox; Green chemistry;
With sodium hydroxide; In toluene; for 1h; Green chemistry;
With lithium aluminium tetrahydride; In tetrahydrofuran; at 0 ℃; for 1h;
443 mg

5344-27-4 Upstream products

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    picoline

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    50-00-0

    formaldehyd

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    29800-89-3

    methyl 4-pyridineacetate

  • 54401-85-3
    54401-85-3

    pyridin-4-yl-acetic acid ethyl ester

5344-27-4 Downstream products

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    benzoic acid-(2-[4]pyridyl-ethyl ester)

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    109262-12-6

    4-(2-hydroxy-ethyl)-1-phenacyl-pyridinium; bromide

  • 622-26-4
    622-26-4

    4-(2-Hydroxyethyl)piperidine

  • 100-43-6
    100-43-6

    4-vinylpyridine

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