(6R,7R)-3-(Acetoxymethyl)-8-oxo-7-(2-(thiophen-2-yl)acetamido)-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid
- Name (6R,7R)-3-(Acetoxymethyl)-8-oxo-7-(2-(thiophen-2-yl)acetamido)-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid
- CAS 153-61-7
- Purity 99%
Product Details
Quality products?make an important contribution to long-term revenue and profitability. Factory Sells Best Quality (6R,7R)-3-(Acetoxymethyl)-8-oxo-7-(2-(thiophen-2-yl)acetamido)-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid 153-61-7 with stock
1.What is the (6R,7R)-3-(Acetoxymethyl)-8-oxo-7-(2-(thiophen-2-yl)acetamido)-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid ?
A first generation cephalosporin antibiotic with a wide range antibacterial activity. It is effective against gram-positive and gram-negative bacteria, and has been tested in respiratory disease and neuromuscular junction studies.Cephalothin is most effective against Gram-positive cocci and is also effective against several Gram-negative organisms. First generation cephalosporins are used primarily to treat skin and soft tissue infections caused by Staphylococcus and Streptococcus species. Cephalothin is ineffective against enterococci and evidence of in vitro sensitivity should be discounted.
-
-
39098-97-0
2-thienylacetic acid chloride
-
-
957-68-6
7-Aminocephalosporanic acid
-
-
153-61-7
cephalothin
| Conditions | Yield |
|---|---|
|
7-Aminocephalosporanic acid;
With
N,O-bis-(trimethylsilyl)-acetamide;
In
dichloromethane;
at 25 - 30 ℃;
Inert atmosphere;
2-thienylacetic acid chloride;
In
dichloromethane;
at 10 ℃;
for 1h;
Temperature;
Solvent;
Reagent/catalyst;
Inert atmosphere;
|
92%
|
|
With
N,O-bis-(trimethylsilyl)-acetamide;
In
acetonitrile;
Inert atmosphere;
|
85%
|
|
With
tetrabutylammomium bromide; sodium hydrogencarbonate;
In
dichloromethane; water;
at -5 - 0 ℃;
Temperature;
|
|
|
With
sodium hydrogencarbonate;
In
water;
at 15 - 30 ℃;
for 1h;
Solvent;
Temperature;
|
-
-
1918-77-0
Thiophene-2-acetic acid
-
-
957-68-6
7-Aminocephalosporanic acid
-
-
153-61-7
cephalothin
| Conditions | Yield |
|---|---|
|
With
1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine;
In
dichloromethane;
at 30 ℃;
for 2h;
Time;
Reagent/catalyst;
Green chemistry;
|
85%
|
2.What is the CAS number for (6R,7R)-3-(Acetoxymethyl)-8-oxo-7-(2-(thiophen-2-yl)acetamido)-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid ?
The CAS number of (6R,7R)-3-(Acetoxymethyl)-8-oxo-7-(2-(thiophen-2-yl)acetamido)-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid is 153-61-7.
More information of (6R,7R)-3-(Acetoxymethyl)-8-oxo-7-(2-(thiophen-2-yl)acetamido)-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid 153-61-7 are:
|
CAS?Number |
153-61-7 |
|
Density |
1.569 g/cm3 |
|
Melting Point |
160-161 °C |
|
Boiling Point |
757.222 °C at 760 mmHg |
|
Flash Point |
411.753 °C |
|
Vapor Pressure |
4.25E-24mmHg at 25°C |
|
Refractive Index |
1.6510 (estimate) |
|
PSA |
166.55000 |
|
LogP |
0.92110 |
|
Pka |
pKa 2.5 (Uncertain) |
3.What are another words for (6R,7R)-3-(Acetoxymethyl)-8-oxo-7-(2-(thiophen-2-yl)acetamido)-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid ?
Synonyms?for?(6R,7R)-3-(Acetoxymethyl)-8-oxo-7-(2-(thiophen-2-yl)acetamido)-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid 153-61-7:5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid,3-[(acetyloxy)methyl]-8-oxo-7-[(2-thienylacetyl)amino]-, (6R,7R)- (9CI);5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid,3-[(acetyloxy)methyl]-8-oxo-7-[(2-thienylacetyl)amino]-, (6R-trans)-;3-(Acetoxymethyl)-8-oxo-7-[2-(2-thienyl)acetamido]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid;3-Acetoxymethyl-7-(2-thienylacetamido)-3-cephem-4-carboxylic acid;7-(2-Thienylacetamido)cephalosporanic acid;7-(Thiophene-2-acetamido)cephalosporin;7-[2-(2-Thienyl)acetylamido]cephalosporanic acid;
4.What is the molecular formula of (6R,7R)-3-(Acetoxymethyl)-8-oxo-7-(2-(thiophen-2-yl)acetamido)-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid?
The chemical formula of ?(6R,7R)-3-(Acetoxymethyl)-8-oxo-7-(2-(thiophen-2-yl)acetamido)-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid is?C16H16N2O6S2 which containing 16 Carbon atoms,16 Hydrogen atoms,2 Nitrogen atoms,6 Oxygen atoms and 2 Sulfur atoms,and the molecular weight of??(6R,7R)-3-(Acetoxymethyl)-8-oxo-7-(2-(thiophen-2-yl)acetamido)-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid?is 396.445.
5.What is (6R,7R)-3-(Acetoxymethyl)-8-oxo-7-(2-(thiophen-2-yl)acetamido)-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid (153-61-7) used for?
Cephalothin is a semisynthetic, beta-lactam, first-generation cephalosporin antibiotic with bactericidal activity. Cephalothin binds to and inactivates penicillin-binding proteins (PBP) located on the inner membrane of the bacterial cell wall. PBPs participate in the terminal stages of assembling the bacterial cell wall, and in reshaping the cell wall during cell division. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This results in the weakening of the bacterial cell wall and causes cell lysis.
InChI:InChI=1/C16H16N2O6S2/c1-8(19)24-6-9-7-26-15-12(14(21)18(15)13(9)16(22)23)17-11(20)5-10-3-2-4-25-10/h2-4,12,15H,5-7H2,1H3,(H,17,20)(H,22,23)/t12-,15-/m0/s1
Relevant articles related to (6R,7R)-3-(Acetoxymethyl)-8-oxo-7-(2-(thiophen-2-yl)acetamido)-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid:
|
Article |
Source |
|
Preparation method of cefoxitin lactone |
- Paragraph 0011; 0044-0045; 0051-0052; 0055-0056, (2020/02/08) |
|
Application of cefoxitin sodium pharmaceutical preparations in preoperative infection prevention for transvaginal hysterectomy, laparoscopic hysterectomy and cesarean section |
- Paragraph 0168-0169; 0174-0175; 0180-0181; 0202-0203, (2019/11/13) |
6.Buy (6R,7R)-3-(Acetoxymethyl)-8-oxo-7-(2-(thiophen-2-yl)acetamido)-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid with the best price .
HEBEI DEZHENG CHEMICALS CO.,LTD is a quality supplier of (6R,7R)-3-(Acetoxymethyl)-8-oxo-7-(2-(thiophen-2-yl)acetamido)-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid. Our main goal is customer satisfaction. Contact us to negotiate the best price for your business on (6R,7R)-3-(Acetoxymethyl)-8-oxo-7-(2-(thiophen-2-yl)acetamido)-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid 153-61-7.
Related products
-
MOLYBDENUM(III) BROMIDE
CAS:13446-57-6
-
2-(bicyclo[2.2.1]hept-5-en-2-ylmethylene)hexenal
CAS:38284-44-5
-
MARITIMEIN
CAS:490-54-0
-
N-METHYL-2-NITROANILINE
CAS:612-28-2