(2-butylbenzofuran-3-yl) (4-methoxyphenyl) ketone
- Name (2-butylbenzofuran-3-yl) (4-methoxyphenyl) ketone
- CAS 83790-87-8
- Purity 99%
Product Details
Factory supply (2-butylbenzofuran-3-yl) (4-methoxyphenyl) ketone 83790-87-8 with sufficient production capacity
- Molecular Formula: C20H20 O3
- Molecular Weight: 308.377
- Vapor Pressure: 4.43E-09mmHg at 25°C
- Boiling Point: 472°C at 760 mmHg
- Flash Point: 239.3°C
- PSA： 39.44000
- Density: 1.124g/cm3
- LogP: 5.01500
(2-butylbenzofuran-3-yl) (4-methoxyphenyl) ketone(Cas 83790-87-8) Usage
|
General Description |
(2-butylbenzofuran-3-yl) (4-methoxyphenyl) ketone, also known as 2-(2-butylbenzofuran-3-yl)-1-(4-methoxyphenyl)ethanone, is a chemical compound with a complex and specific structure. It is often used in the synthesis of pharmaceuticals and other organic compounds due to its unique molecular configuration. The compound contains a ketone group and a benzofuran ring, which makes it useful for applications in medicinal chemistry and drug discovery. Additionally, the presence of a methoxyphenyl group adds further versatility to its chemical properties. Overall, this compound has the potential for various applications in the field of organic chemistry and drug development. |
InChI:InChI=1/C20H20O3/c1-3-4-8-18-19(16-7-5-6-9-17(16)23-18)20(21)14-10-12-15(22-2)13-11-14/h5-7,9-13H,3-4,8H2,1-2H3
83790-87-8 Relevant articles
Discovery of dronedarone and its analogues as NLRP3 inflammasome inhibitors with potent anti-inflammation activity
Chen, Hao,Chen, Xiuhui,Sun, Ping,Wu, Dan,Yue, Hu,Pan, Jintao,Li, Xinxuan,Zhang, Cheng,Wu, Xinyi,Hua, Lei,Hu, Wenhui,Yang, Zhongjin
supporting information, (2021/06/18)
Inhibiting NLRP3 inflammasome activation...
Benzofuran compound and application thereof
-
Paragraph 0053-0057; 0062-0063; 0106-0107, (2021/08/06)
The invention provides a benzofuran comp...
Preparation method of amiodarone hydrochloride key intermediate
-
Paragraph 0030-0031; 0033-0034; 0036-0037; 0039-0040; 0042, (2021/11/03)
The invention discloses a preparation me...
Preparation method of amiodarone hydrochloride
-
Paragraph 0014, (2019/08/12)
The invention relates to a preparation m...
83790-87-8 Process route
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![2-n-butylbenzo[b]furan](/upload/2026/10/93ffcf5bdd5347cdb1f2c97cc02df445_95da7859-f20d-4972-b196-13fe44eb29da.png)
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4265-27-4
2-n-butylbenzo[b]furan
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100-07-2
4-methoxy-benzoyl chloride
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-
83790-87-8
2-n-butyl 3-(4-methoxy benzoyl)-benzofuran
| Conditions | Yield |
|---|---|
|
With
aluminum (III) chloride;
In
1,2-dichloro-ethane;
at -20 - -10 ℃;
Solvent;
Temperature;
Reagent/catalyst;
Large scale;
|
81.2%
|
|
With
aluminum (III) chloride;
In
dichloromethane;
at 20 ℃;
for 24h;
Inert atmosphere;
|
71%
|
|
2-n-butylbenzo[b]furan;
With
carbon disulfide;
for 0.5h;
Inert atmosphere;
Cooling with ice;
4-methoxy-benzoyl chloride;
With
tin(IV) chloride;
at 0 - 20 ℃;
for 75h;
|
64%
|
|
4-methoxy-benzoyl chloride;
With
aluminum (III) chloride;
In
dichloromethane;
at 0 - 5 ℃;
for 1h;
2-n-butylbenzo[b]furan;
In
dichloromethane;
at 5 - 25 ℃;
for 2h;
|
10.6 g
|
-
-
75-44-5
phosgene
-
-
4265-27-4
2-n-butylbenzo[b]furan
-
-
75-34-3
1,1-dichloroethane
-
-
83790-87-8
2-n-butyl 3-(4-methoxy benzoyl)-benzofuran
| Conditions | Yield |
|---|---|
|
With
sodium hydrogencarbonate;
aluminium chloride;
In
water; methoxybenzene;
|
78.7%
|
83790-87-8 Upstream products
-
75-44-5
phosgene
-
4265-27-4
2-n-butylbenzo[b]furan
-
75-34-3
1,1-dichloroethane
-
100-07-2
4-methoxy-benzoyl chloride
83790-87-8 Downstream products
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52490-15-0
2-n-Butyl-3-(4-hydroxy-benzoyl)-benzofuran
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1951-26-4
2-n-butyl-3-(3',5'-diiodo-4'-hydroxybenzoyl)benzofuran
-
1951-25-3
Amiodarone
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19774-82-4
amiodarone hydrochloride
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